Characterisation of M2e Antigenicity using anti-M2 Monoclonal Antibody and anti-M2e Polyclonal Antibodies
نویسندگان
چکیده
منابع مشابه
Development and ELISA-based detection of anti-M2e IgY antibodies using an encoding plasmid for M2e-Hsp70 C-terminal gene
Background: The use of IgYs in a variety of methods in different areas of research, diagnostics, medical application and biotechnology should be considered widely. Objectives: Development of antibodies against extra cellular domain of influenza M2 (M2e) protein in egg yolk of laying hens. Methods: A Fusion construct harboring C-terminal of bovine heat shock protein 70 (Hsp70) and influenza M2e ...
متن کاملEfficacy and safety of treatment with an anti-m2e monoclonal antibody in experimental human influenza.
BACKGROUND The efficacy of TCN-032, a human monoclonal antibody targeting a conserved epitope on M2e, was explored in experimental human influenza. METHODS Healthy volunteers were inoculated with influenza A/Wisconsin/67/2005 (H3N2) and received a single dose of the study drug, TCN-032, or placebo 24 hours later. Subjects were monitored for symptoms, viral shedding, and safety, including cyto...
متن کاملdevelopment and elisa-based detection of anti-m2e igy antibodies using an encoding plasmid for m2e-hsp70 c-terminal gene
background: the use of igys in a variety of methods in different areas of research, diagnostics, medical application and biotechnology should be considered widely. objectives: development of antibodies against extra cellular domain of influenza m2 (m2e) protein in egg yolk of laying hens. methods: a fusion construct harboring c-terminal of bovine heat shock protein 70 (hsp70) and influenza m2e ...
متن کاملGeneration of Egg Yolk Antibodies in Chicken ( IgY ) Against Influenza M 2 ( M 2 e ) Protein
Chicken egg yolk immunoglobulins (IgY) from immunized hens have considerable advantages for the production of polyclonal antibodies. It reacts with more epitopes and avoids the interference in immunological assays. Regarding the IgY aptitudes, this study was conducted to produce chicken IgY specific for influenza M2 (M2e) protein. Fusion construct harboring C-terminal of bovine heat shock prote...
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ژورنال
عنوان ژورنال: Jurnal Ilmu Ternak dan Veteriner
سال: 2019
ISSN: 2252-696X,0853-7380
DOI: 10.14334/jitv.v24i3.1987